Collaborate with the PE&MS Team to design and execute experimental projects under the supervision of direct managers and scientific project leads.
Utilize recombinant protein display systems, such as yeast, mammalian, or phage display, for various protein engineering applications.
Apply molecular biology techniques, including DNA isolation and purification from yeast and/or E. coli, PCR, and DNA transformation, to design and construct DNA libraries.
Use FACS and MACS to enrich libraries of displayed molecules for phenotypes of interest and analyze target binding profiles.
Maintain and implement good laboratory practices, including accurate laboratory notebook (ELN) documentation, instrument and reagent validation, and adherence to lab safety policies.
Regularly present data and analysis at cross-disciplinary team meetings and develop and maintain professional relationships to drive projects forward.
Qualifications:
B.S. or M.S. in Biochemistry, Biology, Bioengineering, Immunology, or a similar field.
2 – 4+ years of academic or biotech/pharma laboratory experience.
Strong preference for experience with protein display technologies (e.g., yeast, phage).
Demonstrated understanding of complex molecular biology techniques, such as PCR, primer design, DNA purification, DNA library design and construction using multiple methods (golden gate cloning, Gibson assembly, SOE), and maintenance and culture of yeast and E. coli.
Quick learner with the ability to understand the significance of new lab techniques to program goals.
Highly motivated to drive the generation of experimental data at the bench.
Knowledge of oncology or immunology is beneficial.
Strong organizational skills, excellent attention to detail, and data analysis skills.
Ability to work independently as well as collaboratively within a team.
Proficiency with Microsoft Excel, PowerPoint, and Word; experience with FlowJo and SnapGene preferred.
Enjoys working in a collaborative, fast-paced, and dynamic environment.
